IndraLab

Statements

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"Therefore our results suggest that the anti-inflammatory effect of PA is due to inhibit the caspase-1 activation."
23213315
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"ATF4 knockdown also led to marked suppression of PA-induced caspase-1 cleavage and IL-1β secretion (Figures 2E and 2F, Online Figure 2C)."
30871699
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"PA-mediated caspase-1 activity was inhibited by DHA in 3T3-L1 preadipocytes transfected with control shRNA or by knockdown of GSK-3β in cells transfected with GSK-3β shRNA (Figure 7B)."
36234919
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"Palmitate induced degradation of pro-caspase-1 to caspase-1 (p10) as well as cleavage of pro-IL-1beta to mature IL-1beta in primary mouse hepatocytes, as determined by immunoblotting of caspase-1 (p10) and IL-1beta in cell supernatants (XREF_FIG)."
27075683
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"Consistent with these previous studies, our data demonstrate that palmitate induced caspase-1 activity and IL-1beta production were blocked by cathepsin B inhibitor Ca-074Me."
27689324
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"Figure 5B illustrates effect of SIRT1 on PA-decreased caspase-1 activity."
38543036
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"PA also suppressed the activation of caspase-1."
23213315