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USP5 activates Hyperalgesia. 1 / 1

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"Importantly, the authors showed that prophylactic knockdown of USP5, or prophylactic disruption of the Ca 3.2/USP5 complex, was sufficient to prevent nerve-injury-induced mechanical and thermal hyperalgesia demonstrating the causal implication of the ubiquitinylation machinery in the development of neuropathic pain in this experimental model."

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USP5 activates Hyperalgesia. 1 / 1

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