IndraLab

Statements


USP14 activates ATF2. 2 / 2
| 2

reach
"In the present study, we identified USP14 as a novel ATF2 interacting protein by IP/MS assay and found that USP14 promoted the transcriptional activity and expression of ATF2 downstream target genes b[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

reach
"Hence, the USP14-induced enhancement in PC development through the stabilization of AR validated its potential role in PC therapy.Furthermore, USP14 was found to upregulate the abundance and transcriptional activity of activating transcription factor 2 (ATF2), which function as both a transcription factor and oncogene in PC, via its deubiquitination (Ma et al., 2018), thus enhancing the proliferation of PC cells."