IndraLab

Statements


USP14 activates ATF2. 3 / 3
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sparser
"USP14 deubiquitinates and activates ATF2, resulting in enhanced prostate cancer cells proliferation both in vitro and in vivo."

reach
"Hence, the USP14-induced enhancement in PC development through the stabilization of AR validated its potential role in PC therapy.Furthermore, USP14 was found to upregulate the abundance and transcriptional activity of activating transcription factor 2 (ATF2), which function as both a transcription factor and oncogene in PC, via its deubiquitination (Ma et al., 2018), thus enhancing the proliferation of PC cells."

reach
"USP14 deubiquitinates and activates ATF2, resulting in enhanced prostate cancer cells proliferation both invitro and invivo."