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"Hence, the USP14-induced enhancement in PC development through the stabilization of AR validated its potential role in PC therapy.Furthermore, USP14 was found to upregulate the abundance and transcriptional activity of activating transcription factor 2 (ATF2), which function as both a transcription factor and oncogene in PC, via its deubiquitination (Ma et al., 2018), thus enhancing the proliferation of PC cells."