IndraLab

Statements

CACNA1B binds DPYSL2 and NF1. 3 / 3
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sparser
"Our goal was to identify the component(s) of the CRMP2–neurofibromin interaction that regulate Cav2.2 activity."
28767512
sparser
"Neurons treated with tat-CRMP2/neurofibromin regulating peptide 1 (t-CNRP1) exhibited a decreased Cav2.2 membrane localization, and uncoupling of neurofibromin–CRMP2 and CRMP2–Cav2.2 interactions."
28767512
sparser
"Collectively, these results demonstrate that t-CNRP1 decreases Cav2.2-dependent Ca 2+ influx, currents, and surface localization through disruption of CRMP2’s binding to Cav2.2 and neurofibromin."
28767512