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USP13 inhibits signal transduction. 2 / 2

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"Consistently, it has been reported that deletion of USP13 can activate the NF-κB signaling pathway in response to herpesvirus infection, increasing resistance to the virus (Sun et al., 2017)."

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"Furthermore, knockdown of USP13 upregulated expression level of nuclear accumulation of p65 in BV2 microglia, implying that it activated the NF-κB signaling pathway (Additional file 1: Fig. S6a, b)."

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USP13 inhibits signal transduction. 2 / 2

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