IndraLab

Statements

INS activates KCNMA1. 10 / 10
| 7 3
reach
"However, insulin acts to stimulate BK channel activity and expression, which is blocked by the presence of high glucose."
31196609
reach
"In parallel studies, insulin, applied via the pipette or bath, also activated hSlo channels expressed in HEK293 cells."
15155829
sparser
"Likewise, BK channel activation by insulin is blocked by actin filament stabilization xref ."
20098689
reach
"In contrast, insulin activates K ATP and BK channel by stimulating MAPK."
21856125
sparser
"These data are consistent with BK channel activation by insulin involving MAPK-dependent alterations in actin dynamics."
17298596
reach
"Likewise, BK channel activation by insulin is blocked by actin filament stabilization XREF_BIBR."
20098689
reach
"Furthermore, insulin activation of this pathway enhances BK channel activity by shifting the Ca (2+)-sensitivity such that BK channels are active at more hyperpolarized membrane potentials."
15155829
reach
"In addition, Eun Young Kim 's group investigated insulin modulation of BK channel activity associated with activation of Erk and MAPK and PI3K and Akt signaling pathways in podocytes."
30873046
sparser
"Here we demonstrate that in hippocampal neurons, BK channel activation by insulin is blocked by actin filament stabilization, suggesting that this process is dependent on the actin cytoskeleton."
17298596
reach
"Here we demonstrate that in hippocampal neurons, BK channel activation by insulin is blocked by actin filament stabilization, suggesting that this process is dependent on the actin cytoskeleton."
17298596