IndraLab

Statements


LncRNA increases the amount of USP4. 2 / 2
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"LncRNA H19 targets miR-148a, increases deubiquitinating enzyme USP4 expression, activates the TGF-β signaling pathway in hepatic stellate cells and hepatocytes, and exacerbates hepatic fibrosis 180."

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"LncRNA H19 180 acts as a ceRNA to downregulate the expression of miR-148a and upregulate the expression of USP4, which stabilizes the TGFβRⅠ and activates the TGF-β/smad signaling pathway and promotes the development of liver fibrosis."