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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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USP11 activates NONO. 3 / 3

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"Neither USP11 overexpression nor depletion in SK-Mel-28 and A375 cells had significant influence on NONO mRNA levels, indicating that USP11 positively regulates NONO at the protein levels, but not at the transcriptional levels."

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"As anticipated, overexpression of USP11 could up-regulate NONO in the absence of MG132, whereas MG132 pretreatment effectively eliminated USP11 mediated change of NONO levels."

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"As a result , the knockdown of USP11 decreases NONO levels ."

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USP11 activates NONO. 3 / 3

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