IndraLab

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USP1 deubiquitinates IDs. 2 / 2
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"Deubiquitination of IDs by USP1 promotes ID protein stability and prevents stem cell differentiation."

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"For instance, USP1 slows osteosarcoma proliferation by deubiquitinating the inhibitors of DNA binding proteins (IDs) ID1, ID2, and ID3, in order to maintain a differentiated state in low-aggressive cells [111]."