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Dehydrosoyasaponin-1 activates KCNMA1. 2 / 2
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"In addition, the BK channel beta-subunit-mediated activation by dehydrosoyasaponin-1 (DHS-1) was lost in cells from ZDF rats."

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"Functional studies showed that BK channel activation by dehydrosoyasaponin-1 was diminished and that BK channel mediated vasodilation in response to shear stress was impaired in diabetic coronary arterioles."