IndraLab

Statements

USP9X decreases the amount of KRAS. 4 / 4
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"Also, the KRAS ubiquitination level that was highly reduced by USP9X overexpression returned to the normal level upon NDRG3 depletion (Fig. 5j and Supplementary Fig. 6b)."
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"In addition, depletion of USP9X expression with different siRNAs decreased the endogenous KRAS protein expression in HEK293T cells to the extent comparable to NDRG3 depletion (Supplementary Fig. 5c)."
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"Usp9x KD suppressed NRAS, but not KRAS gene expression (XREF_FIG)."
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"Usp9x KD did not affect the Kras levels in mouse 8041 cells but reduced Kras levels in human MIAPACA2 cells."
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