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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

HCN1 inhibits neuron-restrictive silencer factor. 1 / 1

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"In the kainic acid induced SE model of TLE, downregulation of HCN1 expression in CA1 pyramidal region was caused by an upregulation of a repressing transcription factor, neuron-restrictive silencer factor (NRSF) which suppresses transcription of a number of genes, amongst them the HCN1 gene [XREF_BIBR]."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...