IndraLab

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Mutated ATXN3 activates endoplasmic reticulum. 2 / 2

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"Overexpression of an atx3 mutant defective in deubiquitination inhibits the degradation of misfolded ER proteins and triggers ER stress."

17000876

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"Overexpression of an atx3 mutant that lacks its deubiquitinase activity blocked degradation of at least two ERAD substrates and thus induced ER stress."

| PMC

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IndraLab

Statements

Mutated ATXN3 activates endoplasmic reticulum. 2 / 2

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