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USP2 activates Reactive Oxygen Species. 2 / 2

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"Among the ferroptosis markers, the results showed that USP2 overexpression promoted LDH release, Fe 2+ level, MDA and Lipid ROS, while inhibited GPX4 activity and GSH levels."

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"With regards to myoblasts, the chemical and genetic ablation of USP2 rapidly induces ROS accumulation, with accompanying defects in mitochondrial ATP synthesis [33]."

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USP2 activates Reactive Oxygen Species. 2 / 2

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