IndraLab

Statements

Phosphorylated SRC is active. 8 / 8
8 |
signor
"Ror1 binds to and phosphorylates c-src / ror1 kinase-dependent c-src activation"
22439932
signor
"We found that tcptp dephosphorylates and inactivates src family kinases to regulate t cell responses._"
22080863
signor
"Activation of c-Src by JNK2 was accompanied by the phosphorylation of c-Src on threonine residue (s).|JNK2 directly phosphorylates c-Src and activates its auto phosphorylation."
25377781
signor
"Instead, shh rapidly and locally stimulated phosphorylation of the src family kinase (sfk) members src and fyn in a smo-dependent fashion."
18455992
signor
"Activation of c-Src by JNK2 was accompanied by the phosphorylation of c-Src on threonine residue (s).|JNK2 directly phosphorylates c-Src and activates its auto phosphorylation."
25377781
signor
"Since PTPN2 dephosphorylates and inactivates Src [ xref ], the increase of pY439 might have resulted from reduced dephosphorylation or elevated Src activity or both."
33603165
signor
"Mechanistically, RIL suppresses Src activation through interacting with Src and PTPL1, allowing PTPL1 dependent dephosphorylation of Src at the activation loop.|Our results reveal a novel Src inactivation cycle in which reversion-induced LIM preferentially recognizes active Src and facilitates PTPL1-mediated inactivation of Src."
19307596
signor
"Collectively, these results suggest that PTPRB inhibits Src activation and down -- regulation of PTPRB activates Src signalling pathway required for cell invasion in A549 cells.|Knockdown of PTPRB increased Src phosphorylation and cell invasion, which was reversed by Src inhibitor PP2."
27314562