IndraLab

Statements


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"Based on this model, EZH2 inhibition was tested in BAP1 inactivated MPMs [ xref ]."

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"The EZH2 inhibitor tazemetostat was administered to patients with BAP1 inactivated MPM (loss of nuclear expression)."

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"In patients with BAP1-inactivated MPM, the disease control rate was 54% (95% CI: 42–67%; 33 of 61 patients) at week 12 after a median follow-up of 35.9 week; no patients had a confirmed complete response and two patients had a confirmed partial response."