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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Caspase inhibits ATXN3. 2 / 2

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"We next asked whether reduction in caspase cleavage modulates Ataxin-3 protein toxicity."

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"In a Drosophila model of SCA3, mutation of proposed caspase cleavage sites in ATXN3 dramatically reduces production of polyQ enriched fragments [XREF_BIBR] and ameliorates degeneration caused by polyQ expanded ATXN3."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...