IndraLab

Statements

PSMD14 inhibits RNF8. 2 / 3

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"BRCC36 and POH1 antagonize the actions of RNF8 and RNF168, hydrolyzing the K63 linkages that promote 53BP1 recruitment."

23554604

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reach

"POH1 is localized to sites of DSBs and can directly antagonize RNF8/RNF168, which collaborate to deposit K63-linked polyubiquitin chains at H2A-type histones in response to damage [129]."

32708614

INDRA sources:

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IndraLab

Statements

PSMD14 inhibits RNF8. 2 / 3

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