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USP30 deubiquitinates MFN1. 2 / 3

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"Additionally, USP30 promotes mitochondrial fusion by deubiquitinating Mfn1 and Mfn2."

35795579

➶

reach

"Specifically, studies performed in HeLa cells overexpressing c-Myc-tagged Ubiquitination Proteasome System (USP) demonstrated that S3 targets a mitochondria-localized deubiquitinase USP30, which mediates deubiquitination of MFN1 and MFN2 and regulates mitochondrial morphology."

35021300

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Statements

USP30 deubiquitinates MFN1. 2 / 3

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