IndraLab

Statements

ITGB1 binds THBS1. 4 / 6
1 | 2 2
sparser
"spaCI not only reveals L–R interactions that are not obvious in the original, sparse seqFISH+ data, but also identifies significant interactions between fibroblast and tumours in with strong L–R interactions such as the THBS1–ITGB1 interaction in lung cancer tissue."
36545790
reach
"Many PTGs were involved in biological processes related to follicular development and ovulation, such as the regulation of progesterone biosynthesis, estrogen metabolism, negative regulation of cell proliferation, ITGA3–ITGB1–THBS1 complex formation, cellular response to transforming growth factor beta stimulus, meiotic cell cycle, and steroid catabolic process (p < 0.05) (Fig. 5A)."
34795345
reach
"From the Sankey plot, we observed prevalent interactions between THBS1/THBS2 and ITGB1 [31], with upstream TFs including SMAD3, JUN and EST1."
36545790
sparser
"Cytoskeletal rearrangements could promote the formation of filopodia, which was shown to be associated with β1 integrin-dependent adhesion to intact THBS1 [ 29 ]."
30439539