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YOD1 activates PML. 3 / 3

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"Blockade of deubiquitinase YOD1 degrades oncogenic PML/RARalpha and eradicates acute promyelocytic leukemia cells."

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"3.1 YOD1 is identified as a key DUB to modulate the stability of the PML/RARalpha protein."

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"Suppression of YOD1 promoted the degradation of PML/RARalpha, thus inhibiting APL cells and prolonging the survival time of APL cell-bearing mice."

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IndraLab

Statements

YOD1 activates PML. 3 / 3

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