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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP6 activates Jak1 stabilization. 1 / 1

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"We envisage that USP6 engenders a potent positive feed-forward immunostimulatory loop as follows ( model , Figure 7B ) : USP6 directly induces Jak1 stabilization / STAT1 activation , leading to low level chemokine production , which we speculate stimulates recruitment of myeloid , NK , and T cells ; these factors may also enhance immune cell activation and proliferation ."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...