IndraLab

Statements

COPS6 activates ptc. 5 / 5
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"In vitro and in vivo data showed that loss of CSN6 attenuated cell proliferation, migration, and invasion of PTC cells, confirming the vital function of CSN6 in PTC."
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"CSN6 promotes PTC progression by inducing the EMT."
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"Second, functional assays showed that CSN6 inhibition significantly reduced both the motility and the proliferation of PTC cells."
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"Thus, loss of CSN6 expression inhibits PTC proliferation and migration."
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"These results suggest that CSN6 robustly modulates PTC migration and invasiveness."
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