IndraLab

Statements

USP8 deubiquitinates HGS. 5 / 5
| 5
reach
"Studies have shown that USP8 also interacts with and deubiquitinate Hrs, demonstrating multiple roles of USP8 in both cargo de-ubiquitination and ESCRT-0 stability during development, which is helpful to address the mechanisms of Hh signaling."
26973699
reach
"Mop recruits Ubpy to promote the deubiquitination of Hrs."
26224310
reach
"Previous studies showed that Hrs is deubiquitinated by Ubpy."
26224310
reach
"USP8 also deubiquitinates and stabilizes HRS and STAM1/2, components of the ESCRT-0 complex, which initially recognizes ubiquitinated plasma membrane proteins and primes their lysosomal sorting on endosomes (Row et al., 2006)."
38180476
reach
"We provide evidence that Ubpy interacts with and deubiquitylates Hrs."
24574010