IndraLab

Statements

USP14 activates translation. 4 / 4
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"TGT inhibition prevents translation of Shigella 's virulence factor, hence reducing pathogenicity."
32515955
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"For example, the deletion of the tRNA guanine transglycosylase gene ( tgt ) responsible for Q modifications reduces the translation of VirF, the transcription factor orchestrating Shigella flexneri vi[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
31295507
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"Mechanistically, YTHDF1 relies on m A modification to promote the translation of frizzled7 (FZD7) and USP14, which transmit WNT/β-catenin signaling and AKT/ERK signaling, respectively (192, 193)."
36999016
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"As a first step towards probing the possibility that TGT may modulate the translation of VirF via modification of the virF mRNA, Michaelis-Menten kinetic analyses were conducted to probe this modification by TGT in vitro."
17626052