IndraLab
Statements
reach
"Because the accumulation of Bag6 * upon USP13 depletion is significantly reduced in cells co-depleted of USP13 and gp78 (XREF_FIG), we propose that USP13 is required to antagonize a promiscuous activity of gp78 towards Ubl4A, which would otherwise impair the function of the Bag6 complex by altering its interaction pattern and/or increasing its cleavage by a cellular protease."