IndraLab

Statements

USP19 activates proteolysis. 4 / 4
| 4
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"USP19 suppresses protein synthesis and enhances protein degradation (ubiquitin proteasome system and autophagy) suggesting that it acts on an upstream signalling pathway (s)."
22476871
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"The deubiquitinating activity of USP19 prevents protein degradation and increases the abundance of both PAH protein variants."
35987969
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"Conclusions : Loss of USP19 suppresses proteolysis upon glucocorticoid stimulation, but enhances protein synthesis upon fasting."
| PMC
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"We found that ectopic expression of USP19 increased PAH protein level, whereas depletion of USP19 promoted PAH protein degradation."
35449354