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USP9X activates JAG1. 1 / 2

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"USP9x in turn stimulates JAG1 activity through two mechanisms : (1) through TRB3 deubiquitination and stabilization, and (2) through deubiquitination and activation of Mind Bomb 1, an E3 ligase required for JAG1 ubiquitination mediated endocytosis and Notch activation."

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USP9X activates JAG1. 1 / 2

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