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Clarithromycin inhibits KCNH2. 5 / 8
1 1 | 5
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"The results of this study document that both erythromycin and clarithromycin significantly inhibit the HERG potassium current at clinically relevant concentrations."
14674677
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"For example, an SNP (Q9E) in MinK-related peptide 1, the putative β subunit of I , has been shown to increase the potency of hERG block by clarithromycin (Abbott et al., 1999)."
35148401
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"Abbott et al. [67] , in an elegant study, were the first to report that clarithromycin could block HERG K + channels.Recently, Volberg et al. compared several macrolides for their ability to block HER[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
15225662
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"Also worth noting is the exclusion from Pred-hERG AD of 11 hERG blockers including namely clarithromycin, digoxin, epinastine, erythromycin, furosemide, fluvoxamine, mexiletine, perhexiline, procainam[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
37468081
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"Clarithromycin, roxithromycin and erythromycin) have been shown to inhibit HERG currents ( Volberg et al., 2002 )."
16647758