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"For example, an SNP (Q9E) in MinK-related peptide 1, the putative b subunit of I Kr , has been shown to increase the potency of hERG block by clarithromycin (Abbott et al., 1999) ."

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"The results of this study document that both erythromycin and clarithromycin significantly inhibit the HERG potassium current at clinically relevant concentrations."

No evidence text available