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Teriflunomide inhibits JAK1. 2 / 2

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"In the same study, teriflunomide inhibited the replication of the H5N1 virus by blocking the activity of Janus kinase 1 (JAK1) and JAK3."

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"12 Furthermore, other proposed mechanisms suggest that teriflunomide inhibits the Janus tyrosine kinase (JAK) enzymes JAK1 and JAK3 13 and reduces transforming growth factor alpha induced nuclear factor kappaB activation."

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IndraLab

Statements

Teriflunomide inhibits JAK1. 2 / 2

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