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USP15 leads to the deubiquitination of DEK. 3 / 3
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"USP15 knockdown increased DEK polyubiquitination and canceled the effect of KIF15 overexpression on reducing DEK polyubiquitination (Figure 3L)."

"KIF15 upregulation promotes leiomyosarcoma cell growth via promoting <span class="match term0">USP15</span>-mediated <span class="match term1">DEK</span> deubiquitylation"

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"Ubiquitination assays showed that USP15 overexpression reduced DEK polyubiquitination and largely abrogated polyubiquitination induced by KIF15 knockdown ( Fig. 3 K)."