IndraLab

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OTUD5 inhibits polB. 2 / 2

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"By inhibiting the FACT-mediated nucleosomal rearrangement and subsequent dimer exchange, which may be possibly reflected in the H2A deposition assay (Figure 5D), OTUD5 may prevent the efficient Pol II progression nearby the damaged chromatin."

30508113

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reach

"OTUD5 localizes to DNA double strand breaks (DSBs), interacts with UBR5 and represses the RNA Pol II elongation and RNA synthesis."

30508113

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IndraLab

Statements

OTUD5 inhibits polB. 2 / 2

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