
IndraLab
Statements
USP39 activates Neoplasm Metastasis. 9 / 9
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"Thus, depletion of USP39 could inhibit the proliferation and metastasis of HCC cells."
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"The depletion of USP39 could inhibit the proliferation and metastasis of HCC cells [11]."
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"Together, these data demonstrate that USP39 knockdown inhibits the metastasis of lung cancer cells in vivo and in vitro."
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"The results showed that USP39 knockdown led to an obvious reduction in tumor metastasis, while TRIM26 downregulation enhanced the tumor metastasis and reversed the reduction of shUSP39-related cell metastasis and the number of nodules in the lung (Fig. 8G, H)."
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"For instance, USP39 promotes colorectal cancer growth and metastasis through the Wnt and beta-catenin pathway [XREF_BIBR]."
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"Moreover, USP39 depletion inhibits HCC cell proliferation and metastasis by promoting ZEB1 degradation."
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"Indeed, silencing USP39 expression markedly inhibited the proliferation and metastasis of HCC cells in vitro and in vivo experiments, indicating the potential carcinogenic effect of USP39 in HCC development."
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"USP39 promotes colorectal cancer growth and metastasis through the Wnt and beta-catenin pathway."