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"Our results demonstrated that ScB treatment reduced MDA level and increased SOD activity and attenuated plasma inflammatory cytokines expression and ScB administration also significantly reduced I/R induced activation of p38MAPK, ERK1/2, and NF-kappaB p65 but not JNK, indicating that the protective role of ScB in this skeletal I/R injury model might be partly mediated through inhibiting p38MAPK, ERK1/2, and NF-kappaB p65 pathways."