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"We found that USP4 promoted the suppressive function of Treg cells by stabilizing interferon regulatory factor (IRF)8. USP4 interacts with and stabilizes IRF8 by deubiquitination of K48-linked polyubi[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

reach
"Taken together, our results suggest that USP4 interacts with and stabilizes IRF8 to promote the suppressive function of Treg cells."