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VEGFA binds PDGFRA. 6 / 9
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"Of note, these pathways were not enriched in VEGFA-PDGFRA -associated gene sets, which instead are involved in cell-junction organization and the HIF-1α transcription factor network (Figs.  xref and  xref ), possibly indicating a coordinated hypoxia-response."
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"In the IDH1 / EGFR -double-WT sample, OPC-like tumor cells interacted with non-tumor cells, including endothelial cells, through ligand-receptor pairs VEGFA-PDGFRA and PDGFA-PDGFRA (Fig.  xref S and T)."
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"VEGF-A 165 bound to both PDGFRalpha and PDGFRbeta."
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"Furthermore, we identified several key ligand-receptor pairs involved in STK24posEpi-to-fibroblast communication: PDGFA-PDGFRA, PDGFA-PDGFRB, BMP2-BMPR2, TGFA-EGFR, VEGFA-PDGFRA, and VEGFA-PDGFRB (Fig.  xref C)."
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"It was found that VEGF-A directly binds to PDGFRα and induce their activations [ xref ]."
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"After VEGF-A 165 stimulation, PDGFR immunoprecipitation, and immunoblot analysis, a distinct association between VEGF-A and PDGFRalpha or PDGFRbeta was demonstrated (XREF_FIG)."
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