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USP12 binds YAP1. 2 / 2

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"Moreover, USP12 interacts with the YAP protein to inhibit its degradation in cancer cells, stabilizing YAP by impeding YAP K48-linked polyubiquitination at the K315 site of YAP ( xref )."

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"Additionally, the Co-IP assay confirmed the interaction between USP12 and YAP (Fig. 6B, C)."

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IndraLab

Statements

USP12 binds YAP1. 2 / 2

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