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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

USP15 activates Multiple Myeloma. 5 / 5

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"Silencing USP15 inhibited MM cell growth both in vitro and in vivo."

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"USP15 knockdown inhibits MM tumor growth and protein expression in vivo."

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"To investigate the role of NF-kappaBp65 signaling in USP15 mediated MM cell proliferation and apoptosis, the NF-kappaBp65 signaling inhibitor PDTC was added to MM cell cultures."

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"PDTC treatment inhibits USP15 overexpression induced MM cell proliferation and apoptosis inhibition."

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"USP15 overexpression promotes MM cell proliferation."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

USP15 activates Multiple Myeloma. 5 / 5

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