IndraLab

Statements



sparser
"In this regard, published cell culture experiments point to Kv1.3 as one such target, showing that FK506 inhibited Kv1.3 in a concentration-dependent manner without suppression of calcineurin protein phosphatase activity."

sparser
"Of particular interest, FK506 inhibited Kv1.3 channels by mechanisms not involving the suppression of calcineurin phosphatase activity, but by a direct interaction with the channel protein ( xref )."