IndraLab

Statements

UCHL5 activates IL1B. 2 / 2
| 2
reach
"We also showed that overexpression of UCH-L5 was associated with a significant increase in caspase-1 activity, while inhibition of UCH-L5 by selective inhibitor [XREF_BIBR] or UCH-L5 knock-down led to decrease in inflammasome dependent IL-1beta release in chicken as well as in human macrophages during infection with Salmonella and during inflammasome activation by lipopolysaccharide (LPS) and nigericin."
26267804
reach
"UCH-L5 inhibition down-regulates IL-1beta release during inflammasome activation in macrophages."
26267804