IndraLab

Statements

Mutated BAP1 inhibits cell death. 2 / 2
| 2
reach
"Subsequent mutations, particularly in genes like CDKN2A, NF2, and TP53, accumulate due to the impaired cell death mechanisms mediated by BAP1 mutations."
39030439
reach
"Based on epidemiological and genetic studies, a carcinogenic model has been proposed in which BRCA1-associated protein 1 mutations are able to suppress cell death in mesothelial cells and increase genomic instability in the mutagenic microenvironment."
34641979