IndraLab

Statements

Ion channel activates CACNA1A. 3 / 3
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"Early linkage studies identified mutations in three independent ion channel genes (CACNA1A, ATP1A2 and SCN1A) that are all causal for FHM ( De Fusco et al, 2003; Dichgans et al, 2005; Ophoff et al, 19[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"In common with the monogenic FHM and MA forms caused by ion channel gene mutations, some ion channel gene loci are implicated in polygenic migraine."
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sparser
"Our data contribute to the accumulating knowledge of voltage-dependent ion channel activation by adding functional information about the effects of so-called non–voltage-sensing residues on VSD dynamics."
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