IndraLab

Statements

SOCS1 inhibits USP18. 2 / 2
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"However, the signaling is negatively regulated by the suppressor of cytokine signaling1 (SOCS1), SOCS3 and ubiquitin-specific peptidase 18 (USP18), which is very important for regulating insulin sensitivity [82–85]."
38312740
reach
"Defects in these negative regulators could lead to the over-activation of positive signal transduction, resulting in disease, such as SOCS1, which negatively regulates the lipopolysaccharide response XREF_BIBR, and USP18, down-regulates the IFN signaling pathway XREF_BIBR."
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