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"Because chloroquine and hydroxychloroquine can effectively prevent systemic lupus erythematosus flare-ups and prevent kidney damage in lupus nephritis,1 2 7 continuous administration of these drugs might benefit patients even if the kidney biopsy reveals zebra body formation and phospholipidosis.In summary, we report 5 patients with lupus nephritis treated with hydroxychloroquine who exhibited a small number of tiny zebra bodies and kidney phospholipidosis."