IndraLab

Statements

Pyrithione activates KCNQ1. 2 / 2
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"Zinc pyrithione (ZnPy) is a potent activator of KCNQ2 and KCNQ3 channels, but also activates KCNQ1 XREF_BIBR, XREF_BIBR."
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sparser
"Several synthetic small-molecule compounds are known to enhance KCNQ1 or KCNQ1/KCNE1 channel functions ( xref ): DIDS and N-phenylanthranilic acid derivatives, such as mefenamic acid, tend to promote KCNQ1/KCNE1 activity ( xref ), whereas zinc pyrithione preferentially activates KCNQ1 in the absence of KCNE1 ( xref )."
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