IndraLab

Statements

USP12 binds BAX. 17 / 17
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reach
"The binding of USP12 to Bax shows the interaction as a DUB, which regulates ubiquitination on Bax."
36361894
reach
"We confirmed the interaction between USP12 and Bax via binding and GST pull-down assays."
36361894
sparser
"The binding of USP12 to Bax shows the interaction as a DUB, which regulates ubiquitination on Bax."
36361894
sparser
"USP12 silencing could induce the upregulation of Bax in prostate cancer by regulating the TP53 signaling pathway [ xref ], and in Hela cells, Bax could bind to USP12 in the nucleus [ xref ]."
37752518
reach
"The diverse regulation of cell proliferation and cell cycle by USP12 indicates its functional diversity and deserves further study.USP12 silencing could induce the upregulation of Bax in prostate cancer by regulating the TP53 signaling pathway [68], and in Hela cells, Bax could bind to USP12 in the nucleus [50]."
37752518
sparser
"We confirmed the interaction between USP12 and Bax via binding and GST pull-down assays."
36361894
biogrid
No evidence text available
36361894
biogrid
No evidence text available
36361894
biogrid
No evidence text available
36361894
biogrid
No evidence text available
36361894
sparser
"Evaluating the results of the yeast two-hybrid (Y2H) screening revealed that ubiquitin-specific protease 12 (USP12) is associated with Bax, and the GST pull-down and binding assays revealed the interaction between Bax and USP12."
36361894
sparser
"We determined that Bax binds to USP12 ( xref A,B)."
36361894
sparser
"Therefore, we conducted experiments on the interaction of USP12 with Bax in the cervical cancer cell line, HeLa."
36361894
reach
"Evaluating the results of the yeast two-hybrid (Y2H) screening revealed that ubiquitin-specific protease 12 (USP12) is associated with Bax, and the GST pull-down and binding assays revealed the interaction between Bax and USP12."
36361894
reach
"We determined that Bax binds to USP12 (Figure 2A,B)."
36361894
reach
"In addition, the GST pull-down assay was performed to check for the interaction between Bax and USP12 (Figure 2D)."
36361894
sparser
"In addition, the GST pull-down assay was performed to check for the interaction between Bax and USP12 ( xref D)."
36361894