IndraLab

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"MYSM1 deficiency spontaneously perturbs the proper repair of DNA damage to accumulate DNA double strand breaks (DSB), accompanied by cellular senescence (Kroeger et al, 2020; Nishi et al, 2014; Tian et al, 2020a)."

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"Therefore, we investigated whether MYSM1 mediates DOX-induced DNA damage in cardiomyocytes by detecting 𝛾 -H2AX."