IndraLab

Statements

CYLD activates NFKB1. 3 / 4
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"CYLD activates NFKB signaling through deubiquitination of NFKB upstream regulators ubiquitylated by cIAP ubiquitin E3 ligase, and inhibition of cIAP by cIAP antagonist blocks NFKB activation XREF_BIBR XREF_BIBR."
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"Cyld inhibits tumor cell proliferation by blocking Bcl3 dependent NFkB signaling."
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"The para-caspase mucosa associated lymphoid tissue (MALT-1) has recently emerged as the most critical regulator of CYLD- mediated NFkB activation in various immune and non immune cells [6-8]."
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