IndraLab

Statements

RIPK2 activates CYLD. 2 / 2
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reach
"In turn, RIPK2 inhibition by siRNA prevented activation of NF-kappaB and ERK1/2 and completely abolished the protective effect of CYLD deficiency with respect to the production of IL-6, NO, ROS, and pathogen control."
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reach
"To study whether increased RIPK2 levels in Cyld -/- BMDM led to the increased activation of NF-kappaB and MAPKs pathways, IFN-gamma-stimulated WT and Cyld -/- BMDM were treated with RIPK2 and control siRNA, respectively, for 48h prior to Lm infection."
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