IndraLab

Statements

LanA1 activates UCHL1. 3 / 3
| 3
reach
"The latent KSHV gene LANA has also been shown to induce UCH-L1, and co-infection has shown that LANA and LMP1 synergize to activate UCH-L1, promoting a tumorigenic phenotype with an increase in proliferation, adhesion, cell migration and apoptosis inhibition [102]."
36560713
reach
"Finally, the mechanism by which LANA and LMP1 induce the uch-l1 promoter was explored."
24314660
reach
"Our findings show that RBP-Jkappa expression enhanced LANA induced activation of the uch-l1 promoter and that endogenous RBP-Jkappa binds to endogenous uch-l1 promoter sequences in transformed B-cells."
24314660